Search results for "crustacean antimicrobial peptides"

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A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii

2022

The defense system of freshwater crayfish Procambarus clarkii as a diversified source of bioactive molecules with antimicrobial properties was studied. Antimicrobial activity of two polypeptide-enriched extracts obtained from hemocytes and hemolymph of P. clarkii were assessed against Gram positive (Staphylococcus aureus, Enterococcus faecalis) and Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria and toward the yeast Candida albicans. The two peptide fractions showed interesting MIC values (ranging from 11 to 700 μg/mL) against all tested pathogens. Polypeptide-enriched extracts were further investigated using a high-resolution mass spectrometry and database search and 14 n…

Microbiology (medical)Infectious Diseasescrustacean antimicrobial peptides; antibiotic resistant strains; high-resolution mass spectrometry; antibiofilm activity; <i>Candida albicans</i>Candida albicansantibiofilm activityPharmacology (medical)crustacean antimicrobial peptideshigh-resolution mass spectrometryGeneral Pharmacology Toxicology and PharmaceuticsBiochemistryMicrobiologyantibiotic resistant strains

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